Gene name:
Slc12a2 (Nkcc1) ;
Protein name:
Solute carrier family 12 member 2 ;
Alternative:
Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 1 ;Basolateral Na-K-Cl symporter ;
Organism:
Mouse (Mus musculus).
General Annotation
Function:
Electrically silent transporter system. Mediates sodium and chloride reabsorption. Plays a vital role in the regulation of ionic balance and cell volume.
Subcellular Location:
Membrane
Multi-pass membrane protein
Protein Attributes:
50:
MEPGPARPRL | APAARPGWGR | AAGCRRRGGP | ARHGRASGQE | DATTAGRQAG |
100:
GGVRGEGTPA | AGDGLGRPLG | PTPSQSRFQV | DPVSENAGRA | AAAAAAAAAA |
150:
AAAAGAAGKE | TPAAGKAGGE | SGVAKGSEEA | KGRFRVNFVD | PAASSSADDS |
200:
LSDAAGVGGD | GPNVSFQNGG | DTVLSEGSSL | HSGGGSGHHQ | QYYYDTHTNT |
250:
YYLRTFGHNT | MDAVPRIDHY | RHTAAQLGEK | LLRPSLAELH | DELEKEPFED |
300:
GFANGEESTP | TRDAVVAYTA | ESKGVVKFGW | IKGVLVRCML | NIWGVMLFIR |
350:
LSWIVGQAGI | GLSVVVIAMA | TVVTTITGLS | TSAIATNGFV | RGGGAYYLIS |
400:
RSLGPEFGGA | IGLIFAFANA | VAVAMYVVGF | AETVVELLKE | HSILMIDEIN |
450:
DIRIIGAITV | VILLGISVAG | MEWEAKAQIV | LLVILLLAIA | DFVIGTFISL |
500:
ESKKPKGFFG | YKSEIFNENF | GPDFREEETF | FSVFAIFFPA | ATGILAGANI |
550:
SGDLADPQSA | IPKGTLLAIL | ITTVVYIGIA | VSVGSCVVRD | ATGNVNDTIT |
600:
TELTNCTSAA | CKLNFDFSYC | ESNTCSYGLM | NNFQVMSMVS | GFAPLISAGI |
650:
FSATLSSALA | SLVSAPKIFQ | ALCKDNIYPA | FQMFAKGYGK | NNEPLRGYIL |
700:
TFLIALGFIL | IAELNVIAPI | ISNFFLASYA | LINFSVFHAS | LAKSPGWRPA |
750:
FKYYNMWISL | IGAILCCIVM | FVINWWAALL | TYVIVLGLYI | YVTYKKPDVN |
800:
WGSSTQALTY | LSALQHSIRL | SGVEDHVKNF | RPQCLVMTGS | PNSRPALLHL |
850:
VHDFTKNVGL | MICGHVHMGP | RRQAMKEMSI | DQARYQRWLI | KNKMKAFYAP |
900:
VHADDLREGA | QYLMQAAGLG | RMKPNTLVLG | FKKDWLQADM | RDVDMYINLF |
950:
HDAFDIQFGV | VVIRLKEGLD | ISHLQGQEEL | LSSQEKSPGT | KDVVVNVDYS |
1000:
KKSDQDTCKS | SGEKSITQKD | EEEDGKTPTQ | PLLKKESKGP | IVPLNVADQK |
1050:
LLEASTQFQK | KQGKNTIDVW | WLFDDGGLTL | LIPYLLTTKK | KWKDCKIRVF |
1100:
IGGKINRIDH | DRRAMATLLS | KFRIDFSDIM | VLGDINTKPK | KENIIAFDDM |
1150:
IEPYRLHEDD | KEQDIADKMK | EDEPWRITDN | ELELYKTKTY | RQIRLNELLK |
1200:
EHSSTANIIV | MSLPVARKGA | VSSALYMAWL | EALSKDLPPV | LLVRGNHQSV |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
ELISA Kit for Mouse Solute carrier family 12 member 2
ELISA Kit for Mouse Solute carrier family 12 member 2
CLIA Kit for Mouse Solute carrier family 12 member 2
CLIA Kit for Mouse Solute carrier family 12 member 2
Polyclonal Antibody for Mouse Solute carrier family 12 member 2
Polyclonal Antibody for Mouse Solute carrier family 12 member 2
Monoclonal Antibody for Mouse Solute carrier family 12 member 2
Monoclonal Antibody for Mouse Solute carrier family 12 member 2
Protein for Mouse Solute carrier family 12 member 2
Protein for Mouse Solute carrier family 12 member 2
R&D Technical Data
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Precision
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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Recovery
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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Linearity
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
2.
"Lineage-specific biology revealed by a finished genome assembly of the mouse."
Church D.M.
,
Goodstadt L.
,
Hillier L.W.
,
Zody M.C.
,
Goldstein S.
,
She X.
,
Bult C.J.
,
Agarwala R.
,
Cherry J.L.
,
DiCuccio M.
,
Hlavina W.
,
Kapustin Y.
,
Meric P.
,
Maglott D.
,
Birtle Z.
,
Marques A.C.
,
Graves T.
,
Zhou S.
,
Teague B.
,
Potamousis K.
,
Churas C.
,
Place M.
,
Herschleb J.
,
Runnheim R.
,
Forrest D.
,
Amos-Landgraf J.
,
Schwartz D.C.
,
Cheng Z.
,
Lindblad-Toh K.
,
Eichler E.E.
,
Ponting C.P.
more...
PLoS Biol.7:E1000112-E1000112(2009)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain :
C57BL/6J .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-259 AND SER-933;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
4.
"The mouse C2C12 myoblast cell surface N-linked glycoproteome: identification, glycosite occupancy, and membrane orientation."
Gundry R.L.
,
Raginski K.
,
Tarasova Y.
,
Tchernyshyov I.
,
Bausch-Fluck D.
,
Elliott S.T.
,
Boheler K.R.
,
Van Eyk J.E.
,
Wollscheid B.
Mol. Cell. Proteomics8:2555-2569(2009)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-544 AND ASN-546
tissue :
Myoblast .